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. 2017 May 9;16(1):192–200. doi: 10.3892/mmr.2017.6553

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Effects of Bruton's tyrosine kinase on NO release and iNOS expression in THS rats. (A) Pulmonary NO concentrations were detected using a commercial kit (n=6 rats/group). iNOS protein expression levels were measured by (B) immunohistochemistry and (C) western blot analysis (n=5 rats/group). Data are expressed as the mean ± standard deviation; **P<0.01 vs. Sham group; ^##P<0.01 vs. THS group. Scale bar, 50 µm. iNOS, inducible NO synthase; LFM-A13, a Bruton's tyrosine kinase inhibitor; NO, nitric oxide; THS, trauma-hemorrhagic shock.