Table I.

Alterations in miRNA expression in liver cells from mice treated with ConA in presence or absence of Gal-9.

A, Upregulated miRNAs
miRNA	P-value	Fold-change, Gal-9/control	Chromosomal localization
mmu-miR-598-5p	0.002	2.507±1.188	8p23.1
mmu-miR-1982-5p	0.019	1.823±0.293	–
mmu-miR-760-5p	0.020	1.777±0.840	1p22.1
mmu-miR-133c	0.044	1.704±0.808	–
mmu-miR-365-3p	0.002	1.636±0.116	–
mmu-miR-361-3p	0.034	1.613±0.227	Xq21.2
mmu-miR-873a-5p	0.006	1.576±0.743	9p21.1
mmu-miR-6405	0.016	1.533±0.731	–
mmu-miR-341-5p	0.041	1.519±0.721	–
mmu-miR-706	0.038	1.513±0.063	14
mmu-miR-544-3p	0.033	1.363±0.644	–
B, Downregulated miRNAs
miRNA	P-value	Fold change, Gal-9/control	Chromosomal localization
mmu-miR-718	0.045	0.564±0.016	X
mmu-miR-1899	0.018	0.576±0.275	–
mmu-miR-6335	0.042	0.621±0.071	–
mmu-miR-127-3p	0.041	0.629±0.140	14q32.2
mmu-miR-181b-5p	0.009	0.633±0.299	–
mmu-miR-331-5p	0.042	0.634±0.304	12q22
mmu-miR-3961	0.041	0.676±0.047	–
mmu-miR-1981-3p	0.008	0.728±0.344	–
mmu-miR-669d-5p	0.030	0.732±0.106	9
mmu-miR-3091-3p	0.044	0.749±0.116	–
mmu-miR-142-5p	0.025	0.755±0.042	17q22
mmu-miR-346-5p	0.029	0.763±0.086	10q23.2

Fold change is presented as the mean ± standard deviation. ‘−’=chromosomal location unclear. miR, miRNA; miRNA, microRNA; ConA, concanavalin A; Gal-9, galectin-9.