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. 2017 May 19;16(1):69–74. doi: 10.3892/mmr.2017.6612

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Copyright: © Wu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Knockdown of AB019562 inhibits proliferation of hepatocellular carcinoma cells. (A) Relative transcript levels of AB019562 in HepG2 cells transfected with specific siRNA against AB019562 (siAB019562). (B) Relative transcription levels of AB019562 in SMMC-7721 cells transfected with siAB019562. (C) Effects of AB019562 knockdown on cell proliferation were assessed over a 5-day period. In HepG2 cells, the proliferation rate was significantly decreased, whereas the level of AB019562 was reduced. (D) Proliferation rate of SMMC-7721 cells was significantly decreased, particularly on days 4 and 5 post-siAB019562 treatment. *P<0.05 vs. control.si/siRNA, small interfering RNA; NC, negative control.