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. 2017 May 25;16(1):609–616. doi: 10.3892/mmr.2017.6629

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Copyright: © Sun et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 6. — TF-microRNA-gene network in LUAD. The regulatory network of TFs (triangles), DEMs (squares) and DEGs (circles); the size of each shape represents the number of closely interacting factors, with the large shapes indicating a higher number of interactions. Red represents upregulated expression in LUAD; blue represents downregulated expression; and yellow is uncertain. Lines denote the regulatory links among these factors. DEG, differential expressed genes; DEM, differential expressed miRNAs; LUAD, lung adenocarcinoma; TF, transcription factor.