Table I.
Association of STIM1, E-cadherin, β-cadherin and MMP-9 expression with characteristics of 170 gastric cancer patients.
| STIM1 | E-Cadherin | β-cadherin | MMP-9 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Positive | Negative | Positive | Negative | Positive | Negative | Positive | Negative | |||||||||
| Characteristic | (74) | (96) | χ2 | P-value | (89) | (81) | χ2 | P-value | (105) | (65) | χ2 | P-value | (88) | (82) | χ2 | P-value |
| Sex | ||||||||||||||||
| Male (127) | 54 (42.5) | 73 (57.5) | 0.208 | 0.648 | 63 (49.6) | 64 (50.4) | 1.52 | 0.218 | 76 (59.8) | 51 (40.2) | 0.79 | 0.375 | 68 (53.5) | 59 (46.5) | 0.64 | 0.43 |
| Female (43) | 20 (46.5) | 23 (53.5) | 26 (60.5) | 17 (39.5) | 29 (67.4) | 14 (32.6) | 20 (46.5) | 23 (53.5) | ||||||||
| Age (years) | ||||||||||||||||
| ≤60 (96) | 45 (46.9) | 51 (53.1) | 1.004 | 0.316 | 48 (50.0) | 48 (50.0) | 0.49 | 0.484 | 55 (57.3) | 41 (42.7) | 1.87 | 0.171 | 45 (46.9) | 51 (53.1) | 2.11 | 0.15 |
| >60 (74) | 29 (39.2) | 45 (60.8) | 41 (55.4) | 33 (44.6) | 50 (67.6) | 24 (32.4) | 43 (58.1) | 31 (41.9) | ||||||||
| Tumor location | ||||||||||||||||
| Cardia (92) | 43 (46.7) | 49 (79.0) | 1.010 | 0.603 | 44 (47.8) | 48 (52.2) | 1.70 | 0.428 | 58 (63.0) | 34 (37.0) | 0.20 | 0.904 | 49 (53.3) | 43 (46.7) | 5.37 | 0.07 |
| Body (11) | 5 (45.5) | 6 (54.5) | 6 (54.5) | 5 (45.5) | 7 (63.6) | 4 (36.4) | 2 (18.2) | 9 (81.8) | ||||||||
| Antrum (67) | 26 (38.8) | 41 (61.2) | 39 (58.2) | 28 (41.8) | 40 (59.7) | 27 (40.3) | 37 (55.2) | 30 (44.8) | ||||||||
| Tumor differentiation | ||||||||||||||||
| Poor/undifferentiated (79) | 32 (40.5) | 47 (59.5) | 0.549 | 0.459 | 37 (46.8) | 42 (53.2) | 1.80 | 0.180 | 54 (68.4) | 25 (31.6) | 2.71 | 0.099 | 45 (57.0) | 34 (43.0) | 1.60 | 0.21 |
| High/moderate (91) | 42 (46.2) | 49 (53.8) | 52 (57.1) | 39 (42.9) | 51 (56.0) | 40 (44.0) | 43 (47.3) | 48 (52.7) | ||||||||
| Tumor size | ||||||||||||||||
| <5 cm (74) | 34 (45.9) | 40 (54.1) | 0.311 | 0.577 | 36 (48.6) | 38 (51.4) | 0.72 | 0.399 | 48 (64.9) | 26 (35.1) | 25.84b | <0.001 | 32 (43.2) | 42 (56.8) | 3.81 | 0.05 |
| ≥5 cm (96) | 40 (41.7) | 56 (58.3) | 53 (55.2) | 43 (44.8) | 57 (59.3) | 39 (40.6) | 56 (58.3) | 40 (41.7) | ||||||||
| Lymphatic metastasis | ||||||||||||||||
| Negative (64) | 10 (15.6) | 54 (84.4) | 32.513b | <0.001 | 22 (34.4) | 42 (65.6) | 13.30b | <0.001 | 16 (25.0) | 48 (75.0) | 58.75b | <0.001 | 16 (25.0) | 48 (75.0) | 29.45b | <0.001 |
| Positive (106) | 64 (60.4) | 42 (39.6) | 67 (63.2) | 39 (36.8) | 89 (84.0) | 17 (16.0) | 72 (67.9) | 34 (32.1) | ||||||||
| Tumor-node-metastasis stage | ||||||||||||||||
| I–II (57) | 17 (29.8) | 40 (70.2) | 6.552a | 0.010 | 18 (31.6) | 39 (68.4) | 14.84b | <0.001 | 20 (35.1) | 37 (64.9) | 25.84b | <0.001 | 27 (47.4) | 30 (52.6) | 0.66 | 0.42 |
| III–IV (113) | 57 (50.4) | 56 (49.6) | 71 (62.8) | 42 (37.2) | 85 (75.2) | 28 (24.8) | 61 (54.0) | 52 (46.0) | ||||||||
Data are expressed as no. (%).
a
P<0.05
b
P<0.01. STIM1, stromal interaction molecule 1; MMP-9, matrix metalloproteinase-9.