Table III.
Blood biochemistry parameters and HOMA indexes in the three experimental groups.
| Parameter | Control group (n=12) | HFD group (n=12) | Octreotide-treated group (n=12) |
|---|---|---|---|
| Plasma glucose (mmol/l) | 4.60±1.17 | 6.26±1.55aa | 4.75±1.60bb |
| Serum insulin (mmol/l) | 118.33±37.08 | 157.68±43.55a | 108.85±66.36b |
| Serum FFA (mmol/l) | 225.36±88.20 | 372.12±125.94aa | 311.11±71.82 |
| Serum TG (mmol/l) | 0.39±0.17 | 0.61±0.23a | 0.50±0.14 |
| Serum TC (mmol/l) | 1.68±0.44 | 2.54±0.62aa | 2.31±0.44 |
| Serum ALT (mmol/l) | 54.35±10.32 | 64.21±9.13aa | 62.80±7.66 |
| Serum AST (mmol/l) | 123.58±11.38 | 143.95±17.68aa | 137.64±16.31 |
| HOMA-index | 23.47±8.86 | 39.57±13.48aa | 23.40±16.71bb |
a
P<0.05
aa
P<0.01 and vs. the control group
b
P<0.05
bb
P<0.01 vs. the HFD group. HFD, high-fat diet; FFA, free fatty acid; TG, serum triglyceride; TC, total cholesterol; ALT, alanine aminotransferase; AST, aspartate aminotransferase; HOMA, homeostatic model assessment.