Table II.

Cox regression model analysis for prognosis based on various clinical characteristics of patients with non-small cell lung cancer.

				miR-124a multivariate analysis
Factor	HR	95% CI (univariate)	P-value	HR	95% CI (multivariate)	P-value
Age	0.96	0.69–1.14	0.45
Gender	0.87	0.53–1.16	0.18
Smoking history	1.21	0.71–1.52	0.19
Lymph-node metastasis	1.72	1.18–2.96	0.03	1.98	1.25–3.03	0.015
Tumor differentiation	0.88	0.54–1.01	0.18
Histology	1.18	0.86–1.21	0.34
TNM stage	1.83	1.56–2.64	0.02	2.13	1.61–2.89	0.009
Invasion of lung membrane	1.22	1.06–1.37	0.15
Vascular invasion	0.98	0.68–1.54	0.31
Diameter	2.56	2.07–5.46	<0.001	3.65	2.26–5.43	<0.001
miR-124a expression	0.68	0.52–0.73	0.023

HR, hazard ratio; miR-124a, microRNA-124a; CI, confidence interval; TNM, tumor node metastasis.