Table II.
Variable | WT sham | FXR−/− sham | WT MI | FXR−/− MI |
---|---|---|---|---|
n | 9 | 9 | 10 | 10 |
EF% | 72.13±0.86a | 70.35±1.13 | 37.64±0.77 | 47.31±1.08b |
FS% | 37.25±0.63a | 38.23±0.76 | 20.63±0.71 | 25.96±0.62b |
LVEDD (mm) | 3.45±0.12a | 3.67±0.11 | 4.78±0.22 | 3.84±0.13b |
LVESD (mm) | 2.09±0.12a | 2.21±0.10 | 3.99±0.12 | 3.10±0.10b |
P<0.05 vs. WT MI group.
P<0.05 vs. WT MI group. WT, wild type; MI, myocardial infarction; FXR, farnesoid X receptor; EF, ejection fraction; FS, fractional shortening; LVEDD, LV end-diastolic diameter; LVESD, LV end-systolic diameter; LV, left-ventricular. Data are expressed as the mean ± standard error of the mean.