Table II.
Differentially expressed genes between human bizarre parosteal osteochondromatous proliferation and osteochondroma, enriched into different molecular function subgroups.
Term | P-value | Genes |
---|---|---|
Growth factor binding | 3.50E-05 | ACVR2A, LTBP1, KLB, INS-IGF2, COL3A1, LIFR, TGFB3, TGFBR3, COL2A1, FGFBP2, ACVR1 |
Glycosaminoglycan binding | 8.50E-05 | LPL, HAPLN1, COMP, LIPG, ACAN, TGFBR3, DCN, ADAMTS3, EPYC, THBS2, PRELP, THBS4 |
Polysaccharide binding | 1.99E-04 | LPL, HAPLN1, COMP, LIPG, ACAN, TGFBR3, DCN, ADAMTS3, EPYC, THBS2, PRELP, THBS4 |
Calcium ion binding | 8.86E-04 | ITGAL, REPS2, LTBP1, S100A8, S100A9, SNCA, ARSJ, MMP7, SPOCK1, EDIL3, CALU, TMEM37, PLCB4, SLC25A25, NPTX2, COMP, AIF1L, ANO2, THBS2, THBS3, THBS4, MATN2, SVEP1, PADI4, MMP14, ITPR1, S100A12, ATP2A2, S100B, SULF1, NOTCH4, RCN3, AOC3 |
Heparin binding | 0.00378 | LPL, COMP, LIPG, TGFBR3, ADAMTS3, THBS2, PRELP, THBS4 |
Transforming growth factor β receptor activity | 0.004672 | ACVR2A, LTBP1, TGFBR3, ACVR1 |
Extracellular matrix structural constituent | 0.006326 | LAMA1, COMP, COL3A1, ACAN, COL12A1, COL2A1, PRELP |
SMAD binding | 0.011707 | FOS, JUN, COL3A1, TGFBR3, ACVR1 |
Transforming growth factor β receptor binding | 0.041652 | TGFB3, TGFBR3, TGFB2 |
Lipid binding | 0.054158 | LPL, RBP7, EPB41, NCF4, SNCA, PPARG, APOLD1, ITPR1, ZCCHC14, BPI, SDPR, FABP4, SCARB1, ARAP2, APOL4 |