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Inhibition of RAGE reduces effect of AGEs on NP cell differentiation, indicating potential pathway of endochondral ossification via the AGE/RAGE axis. (a) Representative images of protein expression determined by western blot of (left) COL10 (58 kDa) and (right) OPN (full length: 66 kDa & MMP cleaved: 32 kDa); (b) quantitative analysis of protein expression normalised to BASAL control (n = 3).
