Table 2. Change in mean probing depth, periodontal attachment level, and intrabony defect and percentage change in bone fill in alendronate and placebo groups from baseline.

Clinical parameters	% change from baseline	ALN group	Placebo group	t- value†	p- value
Mean PD	2 Month 6 Month	2.78 ± 1.20 4.16 ± 1.23	1.24± 0.83 2.05± 0.94	41.01 68.1	<0.001* <0.001*
Mean PAL (mm)	2 Month 6 Month	2.38 ± 0.95 3.95 ± 0.88	0.97 ± 0.92 1.78 ±1.22	41.317 75.789	<0.001* <0.001*
Mean IBD (mm)	6 Month	2.10 ± 0.69	0.12 ± 0.04	302.01	<0.001*
Bone defect fill	6 Month	41.05 ±11.40	2.5 ± 0.93	420.07	<0.001*

*Statistically significant at p<0.05

† t test