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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Osteoarthritis Cartilage. 2016 May 7;24(10):1736–1744. doi: 10.1016/j.joca.2016.05.003

Table III.

Increase of TF JSN ≥0.5 grade by quartile groups of baseline roughness parameters. Lin denotes the linear trend

Birmingham, AL (UAB) computer radiography
Iowa City, IA (Iowa) Digitized film
Medial tibiofemoral JSN increase
Lateral tibiofemoral JSN increase
Medial tibiofemoral JSN increase
30 months
60 months
84 months
60 months
84 months
30 months
No of knees
(increase %)
Adjusted No
OR (95% CI)
No of knees
(increase %)
Adjusted No
OR (95% CI)
No of knees
(increase %)
Adjusted No
OR (95% CI)
No of knees
(increase %)
Adjusted No
OR (95% CI)
No of knees
(increase %)
Adjusted No
OR (95% CI)
No of knees
(increase %)
Adjusted No
OR (95% CI)
Medial bone regions
FSV_S: S = 1.02–1.36 FSV_S: S = 1.02–1.36 FSV_S: S = 1.02–1.36 FSV_L: L = 2.05–2.39 FSV_L: L = 2.05–2.39 FSV_S: S = 0.60–0.80
Q1 (low) 203 (6.9) 1.0 (ref) 192 (12.5) 1.0 (ref) 223 (12.1) 1.0 (ref) 194 (2.6) 1.0 (ref) 223 (3.1) 1.0 (ref) 258 (5.0) 1.0 (ref)
Q2 204 (4.9) 0.70 (0.31–1.54) 193 (13.5) 1.07 (0.58–1.97) 223 (14.8) 1.52 (0.82–2.81) 194 (6.7) 2.93 (1.03–8.35) 223 (7.6) 3.29 (1.26–8.56) 259 (8.1) 1.45 (0.69–3.05)
Q3 204 (6.4) 0.79 (0.36–1.75) 194 (13.4) 0.98 (0.53–1.83) 224 (14.3) 1.42 (0.77–2.63) 195 (7.2) 3.90 (1.39–10.95) 225 (6.7) 3.11 (1.18–8.20) 259 (9.3) 1.93 (0.98–3.78)
Q4 (high) 203 (12.3) 2.09 (1.03–4.22) 193 (19.7) 2.02 (1.14–3.58) 224 (20.1) 2.00 (1.10–3.63) 194 (7.7) 4.37 (1.58–12.10) 223 (9.0) 5.16 (1.94–13.75) 259 (13.1) 2.34 (1.20–4.57)
Trend P = 0.042 (Lin) P = 0.026 (Lin) P = 0.035 (Lin) P = 0.001 (Lin) P = 0.001 (Lin) P = 0.007 (Lin)
FDMEAN: all scales 1.02–2.39 FSV_M: M = 0.90–1.10
Q1 (low) 221 (12.2) 1.0 (ref) 258 (5.4) 1.0 (ref)
Q2 226 (12.8) 1.13 (0.62–2.05) 259 (8.1) 1.52 (0.75–3.05)
Q3 225 (14.2) 1.17 (0.60–2.28) 259 (10.8) 1.94 (1.03–3.67)
Q4 (high) 222 (22.1) 1.91 (1.07–3.39) 259 (11.2) 2.04 (1.02–4.09)
Trend P = 0.025 (Lin) P = 0.028 (Lin)
FSV_L: L = 1.20–1.40
Q1 (low) 258 (6.6) 1.0 (ref)
Q2 259 (7.7) 1.10 (0.52–2.34)
Q3 260 (8.5) 1.56 (0.79–3.08)
Q4 (high) 258 (12.8) 2.26 (1.13–4.54)
Trend P = 0.007 (Lin)
FDV: all scales 0.60–1.40
Q1 (low) 260 (4.6) 1.0 (ref)
Q2 257 (9.3) 1.92 (0.91–4.06)
Q3 260 (7.7) 1.60 (0.77–3.30)
Q4 (high) 258 (14.0) 2.81 (1.41–5.57)
Trend P = 0.007 (Lin)
Lateral bone regions
FSV_S: S = 1.02–1.36
Q1 (low) 223 (9.0) 1.0 (ref)
Q2 224 (9.8) 1.03 (0.53–1.99)
Q3 224 (4.5) 0.45 (0.19–1.03)
Q4 (high) 223 (3.1) 0.32 (0.12–0.82)
Trend P = 0.003 (Lin)
FSV_M: M = 1.53–1.88
Q1 (low) 222 (9.5) 1.0 (ref)
Q2 224 (7.6) 0.88 (0.45–1.74)
Q3 224 (5.8) 0.56 (0.26–1.24)
Q4 (high) 224 (3.6) 0.30 (0.11–0.80)
Trend P = 0.006 (Lin)
FDV: all scales 1.02–2.39
Q1 (low) 226 (10.6) 1.0 (ref)
Q2 220 (7.3) 0.79 (0.40–1.55)
Q3 224 (6.3) 0.66 (0.32–1.35)
Q4 (high) 224 (2.2) 0.27 (0.10–0.73)
Trend P = 0.006 (Lin)

Statistically significant associations are indicated in bold.