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. Author manuscript; available in PMC: 2017 Jun 23.
Published in final edited form as: Int Immunopharmacol. 2015 Aug 24;28(2):1102–1105. doi: 10.1016/j.intimp.2015.07.039

Figure 1.

Figure 1

E4 ameliorates bleomycin-induced pulmonary fibrosis in vivo. A. Representative H&E images of mouse lung tissues treated with E4 and bleomycin (BLM). BLM was intratracheally administrated to male C57BL/6 mice in combination with 20μg oral E4 or scrambled control peptide (Scr). Lungs were harvested 21 days post-treatment. N = 4. Magnification, 100x; B. Lungs were harvested from mice treated with PBS (N=14), BLM (N=14), BLM and E4 (N=9), and BLM and scrambled control peptide (N=8). The amount of collagen in lungs was quantified using hydroxyproline assay. Total collagen was expressed as μg collagen in left lung. C. BAL fluids were collected from mice treated with BLM (N=4) and BLM in combination of E4 (N=4). The number of cells was counted using a hemocytometer.