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. 2017 Jun 23;12(6):e0178420. doi: 10.1371/journal.pone.0178420

Table 2. Induction regimens administered to 1% or more of patients in either squamous or nonsquamous cohorts, by histology and overall.


Induction regimen*
Squamous
(n = 436)
Nonsquamous
(n = 1,578)
All Patients
(N = 2,014)
Carboplatin+pemetrexed 3 (0.7) 405 (25.7) 408 (20.3)
Carboplatin+paclitaxel 164 (37.6) 220 (13.9) 384 (19.1)
Carboplatin+bevacizumab+pemetrexed 0 252 (16.0) 252 (12.5)
Carboplatin+bevacizumab+paclitaxel 4 (0.9) 171 (10.8) 175 (8.7)
Carboplatin+ nab-paclitaxel 92 (21.1) 37 (2.3) 129 (6.4)
Erlotinib 13 (3.0) 58 (3.7) 71 (3.5)
Carboplatin+gemcitabine 51 (11.7) 16 (1.0) 67 (3.3)
Pemetrexed 2 (0.5) 64 (4.1) 66 (3.3)
Carboplatin+docetaxel 21 (4.8) 38 (2.4) 59 (2.9)
Cisplatin+pemetrexed 0 44 (2.8) 44 (2.2)
Docetaxel 6 (1.4) 24 (1.5) 30 (1.5)
Gemcitabine 8 (1.8) 21 (1.3) 29 (1.4)
Carboplatin+etoposide 1 (0.2) 25 (1.6) 26 (1.3)
Cisplatin+etoposide 6 (1.4) 15 (1.0) 21 (1.0)
Carboplatin+bevacizumab+docetaxel 0 16 (1.0) 16 (0.8)
Bevacizumab+pemetrexed 0 16 (1.0) 16 (0.8)
Cisplatin+gemcitabine 11 (2.5) 6 (0.4) 17 (0.8)
Carboplatin+paclitaxel/nab-paclitaxel 10 (2.3) 6 (0.4) 16 (0.8)
Vinorelbine 7 (1.6) 8 (0.5) 15 (0.7)
Paclitaxel 6 (1.4) 11 (0.7) 17 (0.8)
nab-Paclitaxel 5 (1.2) 5 (0.3) 10 (0.5)
Other regimens 26 (6.0) 120 (7.6) 146 (7.2)

Data are n (%).

Abbreviation: nab-paclitaxel, albumin-bound paclitaxel particles

*Induction regimen includes patients who received induction therapy only or patients who received induction followed by continuation maintenance.

”Other” regimens were those received by <1% of patients in each cohort (squamous or nonsquamous)