Table 1. Biochemical profile at 21 days of pregnancy in non-diabetic and diabetic rats not treated or treated with Hibiscus rosa-sinensis aqueous extract during pregnancy.
| Groups | ||||
|---|---|---|---|---|
|
Non-diabetic (n = 12) |
Non-diabetic treated (n = 13) |
Diabetic (n = 12) |
Diabetic treated (n = 11) | |
| TG (mg/dL) | 136.1 ± 14.6 | 195.3 ± 33.6 | 591.3 ± 53.3* | 334.1 ± 104.1# |
| CHO (mg/dL) | 81.3 ± 1.8 | 114.6 ± 15.4 | 143.5 ± 12.3* | 111.6 ± 9.2 |
| HDL-c (mg/dL) | 43.7 ± 2.0 | 24.0 ± 2.4* | 15.3 ± 1.4* | 22.4 ± 1.2# |
| VLDL-c (mg/dL) | 27.2 ± 2.9 | 39.1 ± 6.7 | 118.3 ± 10.6* | 66.8 ± 20.7# |
| AI | 1.0 ± 0.1 | 4.3 ± 0.9* | 8.6 ± 1.4* | 4.6 ± 0.7# |
| CRI | 2.0 ± 0.1 | 5.3 ± 0.9* | 9.8 ± 1.5* | 5.6 ± 0.7# |
| MDA (nM/mg protein) | 92.2 ± 3.0 | 88.2 ± 10.3 | 214.5 ± 8.6* | 183.5 ± 13.4$ |
| SOD (U/mg protein) | 4.6 ± 0.3 | 4.5 ± 0.4 | 4.9 ± 0.4 | 6.4 ±0.6$ |
| GSH-t (U/mg protein) | 13.1 ± 0.5 | 16.6 ± 0.5 | 16.7 ± 1.2 | 15.9 ± 1.1 |
| Thiol groups (mM/mg protein) | 1.2 ± 0.1 | 1.4 ± 0.1 | 1.2 ± 0.1 | 1.1 ± 0.1 |
| CAT (U/mg protein) | 6.5 ± 0.4 | 7.6 ± 1.3 | 4.5 ± 0.5 | 4.0 ± 0.7 |
Data shown as mean ± standard error (SD).
*p < 0.05 compared to non-diabetic group
#p < 0.05 compared to diabetic group
$p < 0.05 compared to non-diabetic treated group (t test).