Table 2. Baseline clinical and biochemical characteristics of the obese subjects according to the conversion of metabolic health during the study period.
MHO at follow-up | MUO at follow-up | ||
---|---|---|---|
Variables | (n = 740) | (n = 1,014) | P value |
Age (year) | 46.9±8.2 | 47.1±8.5 | 0.714 |
Sex (male, %) | 67.3 | 77.1 | <0.001 |
BMI (kg/m2) | 26.6±1.3 | 26.9±1.6 | <0.001 |
WC (cm) | 87.1±10.2 | 88.9±8.9 | <0.001 |
Systolic BP (mmHg) | 112.7±8.2 | 115.5±8.1 | <0.001 |
Diastolic BP (mmHg) | 70.5±6.6 | 72.0±6.5 | <0.001 |
Current smoker (%) | 19.6 | 25.2 | 0.006 |
Moderate drinker (%) | 40.4 | 50.6 | <0.001 |
Physically active (%) | 40.7 | 38.7 | 0.401 |
Family history of diabetes (%) | 16.2 | 17.3 | 0.605 |
FPG (mmol/L) | 5.0±0.3 | 5.1±0.3 | <0.001 |
HbA1c (%) | 5.3 (5.0–5.5) | 5.3 (5.1–5.5) | 0.002 |
Total cholesterol (mmol/L) | 5.0±0.8 | 5.1±0.8 | 0.017 |
TG (mmol/L) | 1.0 (0.8–1.3) | 1.1 (0.9–1.4) | <0.001 |
LDL-C (mmol/L) | 3.2±0.7 | 3.3±0.7 | <0.001 |
HDL-C (mmol/L) | 1.5±0.3 | 1.4±0.3 | <0.001 |
Uric acid (μmol/L) | 5.3±1.3 | 5.7±1.3 | <0.001 |
AST (U/L) | 22 (19–27) | 23 (19–28) | 0.001 |
ALT (U/L) | 21 (15–27) | 23 (18–32) | <0.001 |
GGT (U/L) | 18 (12–27) | 22 (15–33) | <0.001 |
hsCRP (mg/L) | 0.5 (0.3–0.9) | 0.7 (0.4–1.0) | <0.001 |
HOMA-IR | 1.36 (0.98–1.84) | 1.48 (1.09–2.01) | <0.001 |
Data are n (%), median (interquartile range), or mean±SD.