Table 4.
Associations between child urinary BPA, individual, and summed ΣDEHP, ΣHMW, ΣLMW phthalates metabolites with BMI z-score, waist circumference, and sum of skinfolds in children aged 8-14 years old.
| BMI z-score | Waist circumference (cm) | Sum of skinfolds (mm) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
|
|
|||||||||||||
| Analyte | Crude β | (95%CI) | Adj. β | (95%CI) | P-sex interaction | Crude β | (95%CI) | Adj. β | (95%CI) | P-sex interaction | Crude β | (95%CI) | Adj. β | (95%CI) | P-sex interaction |
| BPA | -0.04 | (-0.22, 0.15) | 0.05 | (-0.16, 0.25) | 0.06 | 0.27 | (-1.39, 1.92) | 0.57 | (-1.16, 2.30) | 0.15 | 0.50 | (-1.34, 2.34) | 0.97 | (-1.01, 2.94) | 0.03 |
| MBP | -0.17 | (-0.35, 0.01) | -0.04 | (-0.23, 0.16) | 0.25 | -1.21 | (-2.80, 0.37) | -0.54 | (-2.21, 1.13) | 0.47 | -0.78 | (-2.54, 0.99) | 0.35 | (-1.56, 2.26) | 0.21 |
| MBzP | -0.03 | (-0.23, 0.17) | -0.01 | (-0.23, 0.22) | 0.08 | -0.83 | -2.62, 0.95) | -0.71 | (-2.63, 1.22) | 0.08 | -0.08 | (-2.06, 1.90) | 0.31 | (-1.89, 2.51) | 0.07 |
| MCPP | -0.23 | (-0.42, -0.04) | -0.12 | (-0.32, 0.09) | 0.54 | -1.83 | (-3.50, -0.14) | -1.10 | (-2.88, 0.68) | 0.38 | -1.23 | (-3.10, 0.64) | -0.32 | (-2.36, 1.72) | 0.40 |
| MEP | 0.01 | (-0.10, 0.13) | 0.02 | (-0.11, 0.15) | 0.07 | 0.54 | (-0.49, 1.57) | 0.09 | (-1.04, 1.22) | 0.06 | 0.48 | (-0.66, 1.62) | -0.02 | (-1.32, 1.27) | 0.06 |
| MIBP | -0.10 | (-0.31, 0.10) | -0.07 | (-0.30, 0.16) | 0.54 | -0.97 | (-2.81, 0.87) | -0.61 | (-2.60, 1.37) | 0.72 | -0.48 | (-2.52, 1.57) | -0.22 | (-2.50, 2.05) | 0.79 |
| MEHP | -0.10 | (-0.26, 0.06) | -0.18 | (-0.36, 0.0001) | 0.28 | -0.69 | (-2.16, 0.78) | -1.86 | (-3.36, -0.35) | 0.22 | -1.11 | (-2.73, 0.51) | -2.08 | (-3.80, -0.37) | 0.08 |
| MECPP | -0.01 | (-0.21, 0.18) | -0.06 | (-0.27, 0.14) | 0.02 | -0.77 | (-2.49, 0.94) | -0.91 | (-2.66, 0.83) | 0.04 | -0.51 | (-2.41, 1.40) | -0.71 | (-2.71, 1.29) | 0.03 |
| MEHHP | -0.004 | (-0.19, 0.18) | -0.04 | (-0.24, 0.15) | 0.01 | -0.65 | (-2.26, 0.97) | -0.76 | (-2.42, 0.89) | 0.03 | -0.25 | (-2.04, 1.55) | -0.45 | (-2.35, 1.44) | 0.02 |
| MEOHP | -0.04 | (-0.23, 0.14) | -0.08 | (-0.28, 0.12) | 0.02 | -0.90 | (-2.55, 0.75) | -0.94 | (-2.61, 0.73) | 0.04 | -0.53 | (-2.36, 1.29) | -0.63 | (-2.55, 1.28) | 0.03 |
| ΣDEHP | -0.04 | (-0.23, 0.14) | -0.10 | (-0.28, 0.08) | 0.17 | -0.65 | (-2.17, 0.88) | -1.12 | (-2.65, 0.39) | 0.31 | -0.42 | (-2.11, 1.28) | -0.73 | (-2.48, 1.01) | 0.22 |
| ΣHMW | -0.04 | (-0.21, 0.13) | -0.12 | (-0.30, 0.06) | 0.22 | -0.76 | (-2.32, 0.79) | -1.28 | (-2.83, 0.26) | 0.39 | -0.52 | (-2.25, 1.20) | -0.85 | (-2.62, 0.93) | 0.26 |
| ΣLMW | -0.06 | (-0.23, 0.11) | -0.04 | (-0.20, 0.11) | 0.88 | -0.08 | (-1.33, 1.18) | -0.49 | (-1.83, 0.86) | 0.99 | 0.01 | (-1.38, 1.40) | -0.09 | (-1.63, 1.45) | 0.93 |
N=242 (crude), 194 (adjusted).
All models are adjusted for mother's age, BMI, and years of schooling. Waist circumference and sum of skinfold outcomes are also adjusted for child's age and sex.
Metabolites are SG-corrected and ln-transformed (ng/mL).