Figure 4. The effects of meloxicam treatment on learning and memory of CUMS-treated rats based on the MWM task and the step-down-type passive avoidance test.

a. The escape latency and number of platform crosses in the Morris water maze (MWM) test in CUMS rats after treatment with meloxicam (1 and 3mg/kg, i.g.), sertraline(5mg/kg, i.g.). b. The effects of meloxicam (1 and 3mg/kg, i.g.), sertraline(5mg/kg, i.g.) on the number of errors and latency in the step-down-type passive avoidance test in CUMS-treated rats. Each value represents the mean ± SD, datas for the lantency in MWM were assessed by repeated measures analysis of variance (ANOVA), datas for cross number in MWM and data in step-down-type passive avoidance test were measured by a one-way ANOVA with a Bonferroni correction. **P < 0.01 vs control group. ^# and ^## P < 0.05 and < 0.01 vs the CUMS group. n = 10.