Table 3. Association between CTCs and percentage of different subpopulations of dendritic cells expressing cytokine receptors and co-stimulatory molecules.
Variable | CTC < 1 | CTC > 1 | p - value | CTC < 5 | CTC > 5 | p - value |
---|---|---|---|---|---|---|
Number of patients | 24.0 | 40.0 | NA | 43.0 | 21.0 | NA |
CCR5 in mDC | 55.8 ±5.8 | 63.4 ±4.7 | 0.25 | 61.6 ±4.5 | 57.8 ±6.5 | 0.64 |
CCR5 in pDC | 75.1 ±7.0 | 73.3 ±5.7 | 0.55 | 76.5 ±5.3 | 68.7 ±7.8 | 0.64 |
CCR7 in mDC | 9.6 ±2.5 | 3.2 ±2.0 | 0.46 | 7.1 ±1.9 | 2.7 ±2.8 | 0.21 |
CCR7 in pDC | 2.8 ±1.8 | 1.9 ±1.4 | 0.19 | 2.5 ±1.3 | 1.6 ±2.0 | 0.09 |
CCR5_in_mDC.TLR | 10.9 ±2.8 | 11.2 ±2.3 | 0.20 | 11.8 ±2.1 | 9.3 ±3.3 | 0.16 |
CCR5_in_mDC.US | 21.8 ±3.5 | 18.2 ±2.9 | 0.15 | 20.0 ±2.6 | 18.8 ±4.1 | 0.95 |
CCR5_in_pDC.TLR | 14.5 ±3.0 | 9.0 ±2.4 | 0.02 | 12.7 ±2.3 | 7.6 ±3.5 | 0.23 |
CCR5_in_pDC.US | 22.3 ±4.2 | 14.6 ±3.5 | 0.18 | 18.6 ±3.2 | 15.5 ±5.0 | 0.62 |
CCR7_in_mDC.TLR | 10.6±2.6 | 13.0 ±2.2 | 0.79 | 9.9 ±17.3 | 1.9 ±3.0 | 0.31 |
CCR7_in_mDC.US | 6.1 ±1.8 | 6.2 ±1.5 | 0.76 | 6.1 ±1.4 | 6.3 ±2.1 | 0.75 |
CCR7_in_pDC.TLR | 24.8 ±4.8 | 28.5 ±4.0 | 0.51 | 23.6 ±3.5 | 35.3 ±5.5 | 0.04 |
CCR7_in_pDC.US | 5.3 ±2.2 | 4.2 ±1.8 | 0.72 | 5.7 ±1.6 | 2.1 ±2.6 | 0.23 |
CD80_in_mDC.TLR | 65.8 ± 3.8 | 82.3 ±3.4 | 0.41 | 81.8 ±3.1 | 81.2 ±4.9 | 0.23 |
CD80_in_mDC.US | 18.2 ± 3.1 | 21.9 ±2.6 | 0.65 | 19.0 ±2.3 | 23.7 ±3.7 | 0.82 |
CD80_in_pDC.TLR | 65.8 ± 3.8 | 71.8 ±3.1 | 0.10 | 68.6 ±2.9 | 71.2 ±4.5 | 0.27 |
CD80_in_pDC.US | 3.0 ± 1.3 | 2.5 ±1.1 | 0.55 | 2.4 ±1.0 | 3.4 ±1.5 | 0.96 |
CD86_in_mDC.TLR | 92.6 ± 1.8 | 94.5 ±1.5 | 0.38 | 92.4 ±1.3 | 97.0 ±2.1 | 0.02 |
CD86_in_mDC.US | 86.1 ± 2.8 | 93.7 ±2.3 | 0.07 | 89.2 ±2.2 | 94.0 ±3.4 | 0.16 |
CD86_in_pDC.TLR | 91.5 ± 2.2 | 91.5 ±1.8 | 0.46 | 91.2 ±1.6 | 92.3 ±2.5 | 0.66 |
35.3 ± 4.6 | 38.9 ±3.8 | 0.93 | 33.3 ±3.3 | 47.7 ±5.2 | 0.09 |