Table 6. Prognostic value of different subpopulations of dendritic cells on overall survival in IBC patients.
Variable | HR | 95% Lower CI | 95% Upper CI | p - value |
---|---|---|---|---|
DC | 1.13 | 0.61 | 2.11 | 0.70 |
mDC in DC | 0.63 | 0.34 | 1.17 | 0.14 |
pDC in DC | 0.72 | 0.39 | 1.34 | 0.30 |
CCR5 in mDC | 0.75 | 0.4 | 1.39 | 0.36 |
CCR5 in pDC | 1.02 | 0.55 | 1.9 | 0.95 |
CCR7 in mDC | 1.06 | 0.57 | 1.97 | 0.85 |
CCR7 in pDC | 1.26 | 0.66 | 2.4 | 0.51 |
mDC_TNF-α.TLR | 0.41 | 0.22 | 0.77 | 0.004 |
mDC_TNF-α.US | 0.63 | 0.34 | 1.16 | 0.14 |
pDC_TNF-α.TLR | 0.82 | 0.44 | 1.51 | 0.51 |
pDC_TNF-α.US | 1.91 | 1 | 3.63 | 0.08 |
mDC_IFN-α.TLR | 0.72 | 0.39 | 1.33 | 0.28 |
mDC_IFN-α.US | 1 | 0.54 | 1.85 | 0.99 |
pDC_IFN-α.TLR | 0.79 | 0.43 | 1.47 | 0.45 |
pDC_IFN-α.US | 1.2 | 0.62 | 2.34 | 0.60 |
mDC_IL-12.TLR | 0.92 | 0.49 | 1.72 | 0.79 |
mDC_IL-12.US | 0.6 | 0.32 | 1.13 | 0.11 |
pDC_IL-12.TLR | 0.64 | 0.34 | 1.2 | 0.16 |
pDC_IL-12.US | 1.06 | 0.54 | 2.07 | 0.87 |
mDC_IL-10.TLR | 1.22 | 0.66 | 2.25 | 0.52 |
mDC_IL-10.US | 1.29 | 0.7 | 2.38 | 0.42 |
pDC_IL-10.TLR | 1.1 | 0.59 | 2.03 | 0.77 |
pDC_IL-10.US | 1.4 | 0.76 | 2.6 | 0.27 |
CCR5_in_mDC.TLR | 1.29 | 0.69 | 2.42 | 0.42 |
CCR5_in_mDC.US | 1.54 | 0.82 | 2.9 | 0.17 |
CCR5_in_pDC.TLR | 1.67 | 0.89 | 3.14 | 0.11 |
CCR5_in_pDC.US | 1.35 | 0.72 | 2.55 | 0.34 |
CCR7_in_mDC.TLR | 0.84 | 0.45 | 1.57 | 0.58 |
CCR7_in_mDC.US | 1.19 | 0.63 | 2.23 | 0.59 |
CCR7_in_pDC.TLR | 1.4 | 0.74 | 2.63 | 0.29 |
CCR7_in_pDC.US | 0.91 | 0.48 | 1.71 | 0.77 |
CD80_in_mDC.TLR | 1.04 | 0.56 | 1.96 | 0.89 |
CD80_in_mDC.US | 0.66 | 0.35 | 1.24 | 0.17 |
CD80_in_pDC.TLR | 0.72 | 0.38 | 1.34 | 0.29 |
CD80_in_pDC.US | 0.59 | 0.3 | 1.16 | 0.09 |
CD86_in_mDC.TLR | 0.98 | 0.52 | 1.83 | 0.95 |
CD86_in_mDC.US | 0.66 | 0.35 | 1.25 | 0.20 |
CD86_in_pDC.TLR | 0.66 | 0.35 | 1.25 | 0.19 |
CD86_in_pDC.US | 0.88 | 0.47 | 1.65 | 0.69 |
* all immune cells subpopulation were dichotomized as “low” or “high” based on median value of percentage of immunes cells in all patients. All hazard ratios are based on comparison of “low” vs. “high” groups.