Figure 3. The effect of thalidomide on platelets in vivo.

Thalidomide (200 mg/kg) was intraperitoneally injected into mice followed by collection of peripheral blood at 6 h after administration for analysis of (A) platelet count, (B) platelet surface P-selectin expression and (C) α_IIb expression. (D) Tail bleeding time was also measured. **P < 0.01 (Unpaired student t-test). All the data were acquired from at least three independent experiments.