Table 2. Expression level of miRNAs in the primary tumor and matched liver metastases of 48 colorectal cancer patients with liver metastases.

miRNA	Tumor status	Median	SEM	Foldchange (primary/ metastasis)	p value
miR-513a-5p	Primary	28.9670	7.87524	0.54	0.113
	Metastasis	53.6298	15.04555
miR-181a-5p	Primary	2.2210	1.11954	0.51	0.188
	Metastasis	4.3494	0.99962
miR-182-5p	Primary	19.8616	4.40714	1.48	0.253
	Metastasis	13.3865	4.96276
miR-613	Primary	64.2181	41.80958	1.20	0.877
	Metastasis	53.7233	52.13662
miR-152	Primary	31.6605	18.05150	9.32	0.114
	Metastasis	3.3972	0.93292
miR-644a	Primary	18.0385	9.14903	0.26	0.313
	Metastasis	69.2121	54.83062
miR--550a-5p	Primary	179.4224	87.74360	0.51	0.291
	Metastasis	354.2439	219.88422
miR-196b-5p	Primary	8.8372	4.05013	0.18	0.046*
	Metastasis	49.5967	20.74880
miR-10a-5p	Primary	5.4569	2.19123	0.16	0.062
	Metastasis	33.9821	16.66163
miR-192-5p	Primary	4304.9628	1690.66343	4.77	0.051
	Metastasis	903.1332	275.60286
miR-506-3p	Primary	11.2938	5.02323	1.07	0.908
	Metastasis	10.5453	6.00231
miR-99b-5p	Primary	8.8244	2.75573	6.77	0.007*
	Metastasis	1.3043	0.29901
miR-29a-3p-	Primary	1.3543	0.90819	4.44	0.169
	Metastasis	0.3049	0.18774
miR-27b-3p	Primary	2.6432	0.61204	0.07	0.170
	Metastasis	39.7780	26.64356
miR-377	Primary	92.8067	40.17213	433.47	0.026*
	Metastasis	0.2141	0.13345
miR-200c	Primary	13.4106	3.51479	3.77	0.009*
	Metastasis	3.5561	0.95874
miR-934	Primary	15.6664	11.61170	1.78	0.515
	Metastasis	8.8113	2.47346

Abbreviations: miRNA, microRNA; SEM, standard error of the mean. *p ≤ 0.05.