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. 2017 Mar 15;8(22):35835–35847. doi: 10.18632/oncotarget.16214

Table 1. Results of in silico protein docking of receptors involved in cell proliferation and mammary tumor with LF using HEX-8 software.

S. No. Name of receptor docked with LF protein (1JKY) (B. anthracis) No. of hydrogen bonds Free energy (e-total)
1 Hepatocyte growth factor receptor (c-Met receptor) (3DKC) 19 −773.96
2 Nerve growth factor receptor TrkA (1HE7) 15 −561.83
3 Human Epidermal Growth Factor HER1 (2ITX) 13 −765.30
4 Human Epidermal Growth Factor HER2 (3PP0) 11 −388.29
5 Human Epidermal Growth Factor HER3 (1M6B) 20 −145.42
6 Human Epidermal Growth Factor HER4 (3BCE) 4 −260.00
7 Human Platelet-Derived Growth Factor (1PDG) 7 −577.35
8 Fibroblast Growth Factor Receptor (1FGK) 2 −412.82
9 Protective antigen (B. anthracis) (4H2A) 12 −420.48
10 Protective antigen bound to Anthrax toxin receptor (1T6B) 22 −402.6