Table 4. DNA repair gene haplotypes associated with gastric cancer risk.

Gene	SNPs	Haplotype	Frequency HC	Frequency GC	OR (95% CI)a	P-value
BRIP1	rs2048718	CAC	0.3730	0.4043	Reference
	rs4968451	CAT	0.2021	0.1852	0.85 (0.65–1.1)	0.2203
	rs4986764	TAC	0.1622	0.1609	0.91 (0.69–1.20)	0.5112
		TCT	0.1117	0.0888	0.73 (0.53–0.99)	0.0459
		TCC	0.0621	0.0712	1.07 (0.71–1.62)	0.7384
ERCC4	rs1799801	TGCC	0.5944	0.6408	Reference
	rs1800067	CGGT	0.1857	0.1666	0.83 (0.66–1.03)	0.0927
	rs2238463	CAGT	0.1167	0.1134	0.89 (0.69–1.16)	0.3962
	rs3136038	TGGT	0.0790	0.0599	0.70 (0.50–0.96)	0.0291
ERCC5	rs1047768	CC	0.5330	0.5460	Reference
	rs17655	TG	0.2335	0.1908	0.80 (0.66–0.98)	0.0350
		TC	0.1908	0.2155	1.11 (0.89–1.37)	0.3500
TP53	rs1042522	GCG	0.4331	0.4417	Reference
	rs1614984	GTG	0.2490	0.2939	1.13 (0.92–1.38)	0.2367
	rs9894946	CTG	0.1347	0.1180	0.88 (0.67–1.14)	0.3292
		CCA	0.1222	0.0847	0.68 (0.51–0.91)	0.0081

HC, healthy control; GC, gastric cancer; OR, odds ratio; CI, confidence interval.

Haplotypes with frequencies > 0.05 are shown in the table.

^aOdds ratios and 95% confidence intervals were calculated according to the additive genetic model taking as a reference the more common haplotype.

P-values < 0.05 are highlighted in bold.