Table 1. Detailed characteristics of the patients.
| Patient | Age | Gender | Hepatitis | Serum AFP level (ng/mL) | Metastasis | Glisson capsule invasion | Tumor size (mm) | Differentiation Grade | Multiple liver nodules |
|---|---|---|---|---|---|---|---|---|---|
| P1 | 59 | M | HBV | 670.1 | No | − | 35 | Poorly | - |
| P2 | 50 | M | HBV | 12483 | No | + | 50 | Poorly | - |
| P3 | 37 | M | HBV | 4.47 | No | + | 41 | Poorly | - |
| M1 | 59 | M | HBV | 3.73 | No | − | 6 | moderately | - |
| M2 | 69 | M | HBV | 6.9 | No | + | 160 | moderately | synchronous |
| M3 | 61 | M | NBNC | 1.11 | No | + | 80 | moderately | - |
| W1 | 62 | M | HBV | 266.5 | No | + | 32 | Well | - |
| W2 | 76 | M | HCV | 5.84 | No | + | 70 | Well | - |
| W3 | 19 | F | NBNC | 2.85 | No | − | 29 | Well | - |
| P4 | 48 | M | NBNC | 55.1 | Yes | + | 180 | Poorly | - |
| P5 | 41 | M | HBV | 4.7 | Yes | + | 50 | Poorly | - |
| P6 | 64 | M | HBV | 244.6 | Yes | + | 65 | Poorly | synchronous |
| P7 | 50 | M | HBV | 3.03 | Yes | + | 55 | Poorly | synchronous |
| P8 | 47 | M | HBV | 62.47 | Yes | + | 105 | Poorly | - |
| P9 | 64 | M | HBV | 36541 | Yes | + | 140 | Poorly | - |
| P10 | 52 | M | HBV | 2100 | Yes | − | 35 | Poorly | - |
| P11 | 52 | M | NBNC | 5.3 | No | + | 65 | Poorly | - |
| P12 | 37 | M | HBV | 1810 | No | − | 55 | Poorly | - |
| P13 | 48 | M | HBV | 2.07 | No | − | 35 | Poorly | - |
| P14 | 52 | F | NBNC | 2.45 | No | + | 22 | Poorly | - |
| P15 | 58 | M | HBV | 6.52 | Yes | + | 58 | Poorly | synchronous |
| M4 | 63 | M | HBV | 2975 | No | + | 70 | moderately | synchronous |
| M5 | 47 | M | HBV | 5375 | Yes | + | 130 | moderately | - |
| M6 | 72 | M | HBV | 303.8 | No | + | 40 | moderately | synchronous |
| M7 | 66 | M | HBV | 60500 | No | + | 50 | moderately | - |
| M8 | 59 | M | NBNC | 54.84 | No | + | 26 | moderately | - |
| M9 | 67 | M | HBV | 321.1 | No | + | 55 | moderately | synchronous |
| M10 | 71 | M | HBV | 4606 | Yes | + | 12 | moderately | - |
| M11 | 18 | F | HBV | 37979 | No | + | 70 | moderately | - |
| M12 | 45 | M | HBV | 6528 | No | + | 60 | moderately | synchronous |
| M13 | 61 | M | HBV | 1.9 | No | + | 30 | moderately | - |
| M14 | 52 | M | HBV | 26.53 | No | + | 20 | moderately | - |
| M15 | 58 | F | HBV | 2.55 | Yes | + | 55 | moderately | synchronous |
| M16 | 42 | M | HBV | 3.38 | No | + | 20 | moderately | synchronous |
| M17 | 64 | M | HBV | 774.2 | No | + | 10 | moderately | - |
| M18 | 54 | F | NBNC | 23784 | No | + | 22 | moderately | - |
| W4 | 72 | M | HBV | 11.10 | No | + | 20 | Well | - |
| W5 | 55 | M | HBV | 1.82 | No | + | 34 | Well | - |
| W6 | 76 | M | NBNC | 2.1 | No | + | 34 | Well | - |
| W7 | 67 | M | NBNC | 3.30 | No | − | 18 | Well | - |
| W8 | 50 | M | HBV | 260.9 | No | − | 25 | Well | - |
| W9 | 71 | M | HBV | 11.65 | No | + | 35 | Well | - |
| W10 | 74 | M | NBNC | 5.9 | No | + | 30 | Well | - |
| W11 | 39 | M | HBV | 8.10 | Yes | + | 22 | Well | synchronous |
| W12 | 63 | M | HBV | 208 | No | + | 40 | Well | - |
| W13 | 48 | M | NBNC | 3.07 | No | − | 33 | Well | - |
| W14 | 66 | M | HBV | 82.81 | No | + | 34 | Well | - |
Note: The nine samples used for sequencing are labeled in bold and italic.