Table 3. Top 20 up-regulated genes of poorly differentiated HCC.

Entrez_ID	Gene Symbol	N1	N2	N3	T1	T2	T3	Group mean _exp_N	Group mean _exp_T	Group _log2FC	Group ttest _p value
10130	PDIA6	116.76	123.98	126.57	255.14	260.71	263.04	122.44	259.63	1.08	1.90E-05
578	BAK1	6.41	5.00	9.99	20.24	18.51	23.98	7.14	20.91	1.43	1.03E-04
1650	DDOST	53.21	72.67	59.72	115.80	139.67	121.44	61.87	125.64	1.01	6.57E-04
2786	GNG4	0.04	0.02	0.23	1.84	1.90	2.21	0.10	1.98	1.45	7.97E-04
84933	C8orf76	6.03	5.11	6.90	24.33	21.27	23.79	6.01	23.13	1.78	1.35E-03
22996	TTC39A	0.04	0.29	0.46	2.38	2.35	2.73	0.26	2.49	1.46	1.46E-03
5691	PSMB3	119.36	132.67	145.10	301.66	342.81	347.47	132.37	330.64	1.31	1.74E-03
54522	ANKRD16	1.87	2.67	2.10	6.20	7.28	7.16	2.21	6.88	1.29	2.04E-03
28998	MRPL13	13.72	14.12	18.44	69.51	61.37	73.26	15.43	68.05	2.07	2.62E-03
50854	C6orf48	28.97	70.17	66.97	111.29	140.99	150.56	55.37	134.28	1.26	2.64E-03
3094	HINT1	270.52	305.61	289.43	605.26	590.80	625.23	288.52	607.10	1.07	2.74E-03
4738	NEDD8	131.06	138.11	152.30	291.78	329.80	338.89	140.49	320.16	1.18	2.84E-03
57538	ALPK3	0.47	1.81	1.41	3.16	4.41	3.61	1.23	3.73	1.08	3.65E-03
65244	SPATS2	2.33	3.32	3.91	6.11	7.99	8.07	3.18	7.39	1.00	3.73E-03
8624	PSMG1	15.75	16.67	25.69	37.42	39.74	44.17	19.37	40.44	1.02	4.12E-03
8836	GGH	61.61	26.09	42.65	124.45	87.68	117.67	43.45	109.93	1.32	4.12E-03
23640	HSPBP1	7.35	11.32	9.61	19.05	25.08	24.27	9.42	22.80	1.19	4.27E-03
79075	DSCC1	0.34	0.51	1.13	4.16	4.12	4.17	0.66	4.15	1.63	4.36E-03
5591	PRKDC	5.80	5.46	7.02	17.28	15.77	16.09	6.09	16.38	1.29	4.50E-03
84701	COX4I2	0.22	1.13	0.23	3.16	4.83	3.73	0.53	3.91	1.69	4.56E-03

Note: T1, T2, T3 represent tumor tissue of P1, P2, P3 with poorly differentiated HCC, respectively; N1, N2, N3 represent adjacent non-tumor tissue of P1, P2, P3 with poorly differentiated HCC, respectively.