Table 3. Multivariate COX proportional hazard analysis for PFS of GCs.
| Factors | Surgery alone | Chemotherapy |
|---|---|---|
| HR (95% CI) | HR (95% CI) | |
| sGGT | ||
| low | Reference | Reference |
| high | 0.71(0.39-1.35) | 2.18(1.15-4.47)† |
| Location | ||
| Proximal | Reference | Reference |
| Body | 1.53(0.63-3.73) | 0.98(0.46-2.10) |
| Distal | 0.72(0.37-1.50) | 0.57(0.33-1.05) |
| Whole* | N/A | N/A |
| TNM stage | ||
| Stage I&II | Reference | Reference |
| StageIII&IV | 1.68(0.86-3.52) | 1.42(0.86-2.39) |
| Tumor Grade | ||
| Low | Reference | Reference |
| High | 1.23(0.63-2.38) | 0.84(0.45-1.54) |
| Age (per unit) | ||
| <60 | Reference | Reference |
| >=60 | 0.88(0.51-1.56) | 1.05(0.65-1.71) |
| Gender | ||
| Female | Reference | Reference |
| Male | 1.34(0.73-2.37) | 0.85(0.47-1.47) |
Note: Multivariate COX proportional hazard analysis was conducted to evaluate HR of sGGT1 for PFS of GCs. *Patients in the whole group is not sufficient to do the analysis.
† Statistical significance, p<0.05.