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. 2017 Mar 31;8(22):36289–36304. doi: 10.18632/oncotarget.16749

Figure 6. Tumorigenesis was inhibited by KPNA2 knockdown in a xenograft hepatocellular carcinoma model in nude mice.

Figure 6

(A) Representative images of tumor size in nude mice injected subcutaneously with SMMC-7721 hepatocellular carcinoma cells infected with either Scr-shRNA or KPNA2-shRNA. The tumor volume was examined twice each week, starting from the 10th day after tumor cell injections, for a total of 7 measurements. The mice were killed on the 29th day for tumor weight analysis. (B) Tumor volume examination in nude mice injected subcutaneously with SMMC-7721 hepatocellular carcinoma cells infected with either Scr-shRNA or KPNA2-shRNA. The data shown are the mean ± SEM of the tumor volume from 10 nude mice per group (**p < 0.01). (C) Tumor weight in nude mice injected subcutaneously with SMMC-7721 hepatocellular carcinoma cells infected with either Scr-shRNA or KPNA2-shRNA. The data shown are the mean ± SEM of tumor weight from 10 nude mice per group (**p < 0.01).