Table 3. Stratified analysis of the association between rs6983267 and ovarian cancer risk.
| Variables | Case | Control | OR (95% CI) a | Pa | Pb | ||||
|---|---|---|---|---|---|---|---|---|---|
| TT (%) | GT (%) | GG (%) | TT (%) | GT (%) | GG (%) | ||||
| Age, year | |||||||||
| < 52 | 60 (34.48) | 86 (49.43) | 28 (16.09) | 207 (40.75) | 234 (46.06) | 67 (13.19) | 1.12 (0.85–1.48) | 0.414 | 0.287 |
| ≥ 52 | 68 (33.50) | 97 (47.78) | 38 (18.72) | 187 (35.55) | 276 (52.47) | 63 (11.98) | 1.39 (1.04–1.84) | 0.024 | |
| Age at menarche, year | |||||||||
| < 15 | 56 (32.56) | 83 (48.26) | 33 (19.19) | 82 (36.61) | 113 (50.45) | 29 (12.95) | 1.18 (0.90–1.53) | 0.229 | 0.430 |
| ≥ 15 | 63 (33.69) | 93 (49.73) | 31 (16.58) | 310 (38.41) | 396 (49.07) | 101 (12.52) | 1.40 (1.00–1.94) | 0.050 | |
| Abortion | |||||||||
| Yes | 52 (33.99) | 66 (43.14) | 35 (22.88) | 78 (30.35) | 147 (57.20) | 32 (12.45) | 1.11 (0.81–1.53) | 0.515 | 0.322 |
| No | 68 (33.33) | 110 (53.92) | 26 (12.75) | 281 (40.96) | 327 (47.67) | 78 (11.37) | 1.31 (1.02–1.69) | 0.033 | |
| Menopausal status | |||||||||
| Premenopausal | 36 (28.57) | 65 (51.59) | 25 (19.84) | 186 (40.00) | 221 (47.53) | 58 (12.47) | 1.62 (1.18–2.23) | 0.003 | 0.037 |
| Postmenopausal | 84 (37.50) | 105 (46.88) | 35 (15.63) | 205 (37.55) | 270 (49.45) | 71 (13.00) | 1.05 (0.81–1.35) | 0.733 | |
| Occupation | |||||||||
| Farmer | 53 (34.19) | 77 (49.68) | 25 (16.13) | 145 (37.56) | 200 (51.81) | 41 (10.62) | 1.23 (0.93–1.63) | 0.154 | 0.121 |
| Worker | 14 (24.56) | 33 (57.89) | 10 (17.54) | 76 (45.51) | 73 (43.71) | 18 (10.78) | 1.84 (1.17–2.89) | 0.008 | |
| Other | 61 (36.97) | 73 (44.24) | 31 (18.79) | 173 (35.97) | 237 (49.27) | 71 (14.76) | 1.07 (0.83–1.37) | 0.628 | |
| Oral contraceptive | |||||||||
| Yes | 71 (33.33) | 104 (48.83) | 38 (17.84) | 303 (38.21) | 392 (49.43) | 98 (12.36) | 1.23 (0.97–1.56) | 0.093 | 0.970 |
| No | 52 (34.90) | 70 (46.98) | 27 (18.12) | 82 (37.96) | 108 (50.00) | 26 (12.04) | 1.24 (0.87–1.75) | 0.238 | |
| Family history of cancer | |||||||||
| Yes | 21 (32.31) | 33 (50.77) | 11 (16.92) | 64 (33.68) | 93 (48.95) | 33 (17.37) | 1.09 (0.61–1.93) | 0.774 | 0.593 |
| No | 103 (34.92) | 140 (47.46) | 52 (17.63) | 322 (39.22) | 405 (49.33) | 94 (11.45) | 1.29 (1.03–1.61) | 0.027 | |
a Adjusted for age, age at menarche, abortion, menopausal status, and oral contraceptive where appropriate in additive models.
b P for heterogeneity test.