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3D cell cultured HTS platform using PDCs derived from left and right metastatic lung lesions, respectively (A). A sensitive response by corresponding IC50 values of AZD4547 in giant cell tumor PDCs originated from the right pulmonary nodule under the micropillar/microwell chip platform using 3D culture as compared to left (B and C). The cell proliferation assay in conventional monolayer culture using MTT assay (D).
