Table 4. Univariate and multivariate analysis of factors associated with disease-free survival after pulmonary metastasectomy in rectal cancer.

	Univariate			Multivariate
	HR	(95% CI)	p	HR	(95% CI)	p
No. of lung metastasis			0.008			0.005
Single	1			1
Multiple (≥2)	2.30	(1.25-4.24)		2.34	(1.29-4.24)
DFI to lung metastasis			0.24
≥12 mon	1
<12 mon	1.63	(0.72-3.65)
Size of lung metastasis			0.55
<1cm	1
≥1cm	0.84	(0.47-1.49)
CEA level before lung resection			0.44
Normal	1
Elevated (> 5ng/ml)	1.46	(0.56-3.81)
Adjuvant chemotherapy after lung resection			0.80
No	1
Yes	0.92	(0.49-1.74)

HR = hazard ratio; CI = confidence interval; DFI = disease-free interval; CEA = carcinoembryonic antigen.