Table 1. Particle concentration and stability of BSH loaded liposomes.
| Formulation | Liposome number per ml (× 1013) | 10B atom number per liposome (× 108) | Time (week) | Particle size (nm) | PDI | Zeta potential (mV) | BSH remain entrapped (%) |
|---|---|---|---|---|---|---|---|
| LP | 0 | 123.9 ± 1.8 | 0.10 ± 0.02 | −36.2 ± 0.6 | 100.0 ± 0.8 | ||
| 5.57 ± 1.14 | 2.69 ± 0.49 | 2 | 122.0 ± 1.5 | 0.10 ± 0.02 | −36.9 ± 2.5 | 100.7 ± 1.3 | |
| 4 | 133.5 ± 12.7 | 0.10 ± 0.04 | −34.2 ± 1.5 | 89.2 ± 5.7 | |||
| c(RGDyC)-LP | 0 | 124.5 ± 1.2 | 0.07 ± 0.02 | −46.0 ± 1.0 | 100.0 ± 2.6 | ||
| 6.50 ± 0.55 | 2.23 ± 0.18 | 2 | 124.7 ± 1.6 | 0.07 ± 0.01 | −45.3 ± 1.0 | 100.2 ± 0.8 | |
| 4 | 125.4 ± 1.3 | 0.07 ± 0.02 | −46.7 ± 1.3 | 98.9 ± 1.8 |
Liposomes were stored in pellet form, protected from light and maintained at 4°C (mean ± SD, n=3).