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. 2017 Apr 12;8(22):36664–36673. doi: 10.18632/oncotarget.17067

Table 2. Anti-ENO1 level and area under the curve in different characteristics in validation set.

N median IQR Pa Frequency (%) Pb AUC 95% CI P
Histology
 AD 197 5.42 3.63 0.334 69 (35.0) 0.946 0.579 0.526-0.633 0.003
 SCC 45 5.91 2.98 16 (35.6) 0.630 0.538-0.721 0.005
Stage
 I and II 33 6.00 3.58 0.786 12 (36.4) 0.881 0.596 0.484-0.707 0.073
 III and IV 123 5.55 3.17 43 (35.0) 0.584 0.520-0.647 0.008
Metastasis
 No 122 5.4 3.76 0.799 41 (33.6) 0.618 0.580 0.516-0.645 0.011
 Yes 120 5.62 3.02 44 (36.7) 0.598 0.534-0.661 0.002
Smoking
 No 157 5.71 4.11 0.486 57 (36.3) 0.601 0.599 0.541-0.657 0.001
 Yes 85 5.19 3.07 28 (32.9) 0.570 0.497-0.643 0.051
Gender
 Male 144 5.38 3.3 0.685 49 (34.0) 0.665 0.580 0.52-0.64 0.007
 Female 98 5.75 4.38 36 (36.7) 0.602 0.533-0.671 0.003
Age
 ≤ 60 y 138 5.78 3.7 0.390 50 (36.2) 0.677 0.562 0.495-0.629 0.067
 > 60 y 104 5.34 3.23 35 (33.7) 0.626 0.552-0.700 0.001

AD: Adenocarcinoma; SCC: Squamous Cell Carcinoma; a: Mann-Whitney test; b: χ2 test