Table 4. Characteristics of participants.
| Discovery set | Validation set | |||
|---|---|---|---|---|
| Group | NSCLC (N=20) | Normal (N=20) | NSCLC (N=242) | Normal (N=270) |
| Age, mean ± SD (range) | 63.6 ± 4.5 (53-75) | 64.5 ± 5.3 (55-78) | 58.5 ± 10.5 (27-84) | 58.5 ±10.7 (31-84) |
| ≤ 60 y | 4 (20.0) | 5 (25.0) | 138 (57.0) | 153 (56.7) |
| >60 y | 16 (80.0) | 15 (75.0) | 104 (43.0) | 117 (43.3) |
| Gender | ||||
| Male | 6 (30.0) | 6 (30.0) | 144 (59.5) | 166 (61.5) |
| Female | 14 (70.0) | 14 (70.0) | 98 (40.5) | 104 (38.5) |
| Smoking | ||||
| No | 0 (0.0) | 0 (0.0) | 157 (64.9) | 168 (62.2) |
| Yes | 20 (100.0) | 20 (100.0) | 85 (35.1) | 102 (37.8) |
| Histology | ||||
| AD | 18 (90.0) | 197 (81.4) | ||
| SCC | 2 (10.0) | 45 (18.6) | ||
| Stage | ||||
| I | 20 (100.0) | 20 (8.3) | ||
| II | 0 | 13 (5.4) | ||
| III | 0 | 29 (12.0) | ||
| IV | 0 | 94 (38.8) | ||
| unknown | 0 | 86 (35.5) | ||
| Metastasis | ||||
| No | 16 (80.0) | 122 (50.4) | ||
| Yes | 4 (20.0) | 120 (49.6) | ||
AD: Adenocarcinoma; SCC: Squamous Cell Carcinoma; SD: standard deviation