Table 3. Bivariate and multivariate analysis with DFT in patients with colon cancer.
| ≤30 days | >30 days | Crude analysis | Adjusted analysis* | |||||
|---|---|---|---|---|---|---|---|---|
| n | % | n | % | p | OR 95% CI | p | OR 95% CI | |
| Sex | ||||||||
| Male | 393 | 36.0 | 699 | 64.0 | 0.041 | 1.00 | ||
| Female | 271 | 40.9 | 392 | 59.1 | 0.81 [0.67-0.99] | |||
| Age | ||||||||
| Mean - SD | 68.8 | ±11.3 | 68.8 | ±10.4 | 0.915 | 1.00 [0.99-1.01] | ||
| Marital status | ||||||||
| Single | 38 | 38.0 | 62 | 62.0 | 0.182 | 1.00 | ||
| Married-Cohabiting | 374 | 36.4 | 654 | 63.6 | 1.07 [0.70-1.64] | |||
| Separated-Divorced | 21 | 27.6 | 55 | 72.4 | 1.60 [0.84-3.06] | |||
| Widowed | 97 | 41.3 | 138 | 58.7 | 0.87 [0.54-1.41] | |||
| Education profile | ||||||||
| No education-Primary education | 388 | 34.8 | 726 | 65.2 | 0.001 | 1.00 | 0.008 | 1.00 |
| Secondary-University | 148 | 44.8 | 182 | 55.2 | 0.66 [0.51-0.84] | 0.69[0.52-0.91] | ||
| Currently in work | ||||||||
| No | 396 | 36.9 | 676 | 63.1 | 0.482 | 1.00 | ||
| Yes | 137 | 39.0 | 214 | 61.0 | 0.91 [0.71-1.17] | |||
| BMI | ||||||||
| Mean - SD | 27.2 | ±4.4 | 28.4 | ±5.1 | <0.001 | 1.06 [1.03-1.08] | ||
| Smoking habit | ||||||||
| Never | 332 | 40.0 | 499 | 60.0 | 0.017 | 1.00 | 0.028 | 1.00 |
| Current smoker | 83 | 41.3 | 118 | 58.7 | 0.95 [0.69-1.29] | 1.08[0.74-1.57] | ||
| Ex-smoker | 215 | 33.3 | 430 | 66.7 | 1.33 [1.07-1.65] | 1.40[1.09-1.80] | ||
| Family history of neoplasias | ||||||||
| No | 374 | 37.8 | 616 | 62.2 | 0.952 | 1.00 | ||
| Yes | 220 | 37.9 | 360 | 62.1 | 0.99[0.80-1.23] | |||
| Family history of CRC | ||||||||
| No | 323 | 34.6 | 611 | 65.4 | 0.212 | 1.00 | ||
| Yes | 59 | 39.9 | 89 | 60.1 | 0.80[0.56-1.14] | |||
| Specific signs and symptoms | ||||||||
| Asymptomatic | 40 | 25.0 | 120 | 75.0 | <0.001 | 1.00 | ||
| Moderate signs and symptoms | 132 | 44.0 | 168 | 56.0 | 0.42[0.28-0.65] | |||
| Severe signs and symptoms | 466 | 38.6 | 741 | 61.4 | 0.53[0.36-0.77] | |||
| Size of tumour | ||||||||
| Locally small (T0-T1-T2) | 96 | 25.5 | 280 | 74.5 | <0.001 | 1.00 | <0.001 | 1.00 |
| Locally large (T3-T4) | 555 | 41.4 | 787 | 58.6 | 0.49[0.37-0.63] | 0.51[0.37-0.69] | ||
| Lymph nodes | ||||||||
| Absent | 365 | 35.5 | 663 | 64.5 | 0.015 | 1.00 | ||
| Present | 283 | 41.3 | 402 | 58.7 | 0.78[0.64-0.95] | |||
| Histological diagnosis | ||||||||
| Adenocarcinoma | 585 | 37.6 | 970 | 62.4 | 0.597 | 1.00 | ||
| Mucinous carcinoma | 76 | 39.6 | 116 | 60.4 | 0.92[0.68-1.25] | |||
| Metastasis | ||||||||
| Absent | 523 | 35.3 | 960 | 64.7 | 0.037 | 1.00 | ||
| Present | 63 | 44.1 | 80 | 55.9 | 0.69[0.49-0.98] | |||
| Differentiation | ||||||||
| Low grade | 490 | 36.8 | 843 | 63.2 | 0.223 | 1.00 | ||
| High grade | 86 | 41.1 | 123 | 58.9 | 0.83[0.62-1.12] | |||
| Vascular invasion | ||||||||
| Absent | 475 | 37.7 | 784 | 62.3 | 0.212 | 1.00 | ||
| Present | 98 | 42.1 | 135 | 57.9 | 0.83[0.63-1.11] | |||
| Perineural invasion | ||||||||
| Absent | 426 | 36.6 | 739 | 63.4 | 0.001 | 1.00 | ||
| Present | 137 | 47.2 | 153 | 52.8 | 0.64[0.50-0.83] | |||
| Carcinoembryonic antigen (CEA) | ||||||||
| Normal (0-5) | 324 | 35.3 | 593 | 64.7 | 0.010 | 1.00 | ||
| Abnormal (>5) | 188 | 42.5 | 254 | 57.5 | 0.74[0.58-0.93] | |||
| Cancer antigen 19-9 | ||||||||
| Normal (1-37) | 219 | 35.3 | 401 | 64.7 | 0.011 | 1.00 | ||
| Abnormal (>37) | 56 | 47.9 | 61 | 52.1 | 0.59[0.40-0.89] | |||
| Prior screening | ||||||||
| No | 547 | 41.1 | 783 | 58.9 | <0.001 | 1.00 | <0.001 | 1.00 |
| Yes | 89 | 25.4 | 262 | 74.6 | 2.06[1.59-2.68] | 1.79[1.32-2.43] | ||
| First line of treatment | ||||||||
| Surgery | 643 | 37.8 | 1056 | 62.2 | 0.869 | 1.00 | ||
| Chemotherapy | 20 | 38.5 | 32 | 61.5 | 0.97[0.55-1.72] | |||
| Radiotherapy | 1 | 25.0 | 3 | 75.0 | 1.83[0.19-17.6] | |||
* In multivariate logistic regression with a sample of 1,291 patients