Table 4. Bivariate and multivariate analysis with DFT in patients with rectal cancer.
| ≤30 days | >30 days | Crude analysis | Adjusted analysis* | |||||
|---|---|---|---|---|---|---|---|---|
| n | % | p | OR95% CI | p | OR95% CI | p | OR95% CI | |
| Sex | ||||||||
| Male | 109 | 24.4 | 338 | 75.6 | 0.303 | 1.00 | ||
| Female | 61 | 28.1 | 156 | 71.9 | 0.82[0.57-1.19] | |||
| Age | ||||||||
| Mean - SD | 65.9 | ±11.2 | 67.2 | ±11.0 | 0.168 | 1.01[0.99-1.03] | ||
| Marital status | ||||||||
| Single | 9 | 18.0 | 41 | 82.0 | 0.145 | 1.00 | ||
| Married-Cohabiting | 111 | 27.3 | 295 | 72.7 | 0.58[0.27-1.24] | |||
| Separated-Divorced | 2 | 8.3 | 22 | 91.7 | 2.41[0.48-12.17] | |||
| Widowed | 18 | 26.9 | 49 | 73.1 | 0.60[0.24-1.47] | |||
| Education profile | ||||||||
| No education-Primary education | 97 | 23.3 | 320 | 76.7 | 0.025 | 1.00 | 0.020 | 1.00 |
| Secondary-University | 41 | 33.3 | 82 | 66.7 | 0.61[0.39-0.94] | 0.56[0.34-0.91] | ||
| Currently in work | ||||||||
| No | 107 | 25.4 | 314 | 74.6 | 0.845 | 1.00 | ||
| Yes | 30 | 26.3 | 84 | 73.7 | 0.95[0.60-1.53] | |||
| BMI | ||||||||
| Mean - SD | 26.9 | ±4.1 | 27.1 | ±4.7 | 0.699 | 1.01[0.96-1.05] | ||
| Smoking habit | ||||||||
| Never | 71 | 25.5 | 207 | 74.5 | 0.989 | 1.00 | ||
| Current smoker | 26 | 25.7 | 75 | 74.3 | 0.99[0.59-1.67] | |||
| Ex-smoker | 66 | 25.1 | 197 | 74.9 | 1.02[0.69-1.51] | |||
| Family history of neoplasias | ||||||||
| No | 88 | 25.2 | 261 | 74.8 | 0.757 | 1.00 | ||
| Yes | 70 | 26.3 | 196 | 73.7 | 0.94[0.66-1.36] | |||
| Family history of CRC | ||||||||
| No | 91 | 25.2 | 270 | 74.8 | 0.386 | 1.00 | ||
| Yes | 12 | 20.0 | 48 | 80.0 | 1.35[0.87-2.65] | |||
| Specific signs and symptoms | ||||||||
| Asymptomatic | 4 | 9.1 | 40 | 90.9 | 0.009 | 1.00 | 0.031 | 1.00 |
| Moderate signs and symptoms | 15 | 18.5 | 66 | 81.5 | 0.44[0.14-1.42] | 0.67[0.16-2.74] | ||
| Severe signs and symptoms | 146 | 28.2 | 371 | 71.8 | 0.25(0.09-0.72) | 0.31[0.09-1.07] | ||
| Size of tumour | ||||||||
| Locally small (T0-T1-T2) | 78 | 25.6 | 227 | 74.4 | 0.998 | 1.00 | ||
| Locally large (T3-T4) | 88 | 25.6 | 256 | 74.4 | 1.00[0.70-1.42] | |||
| Lymph nodes | ||||||||
| Absent | 116 | 26.6 | 320 | 73.4 | 0.292 | 1.00 | ||
| Present | 42 | 22.6 | 144 | 77.4 | 1.42[0.83-1.86] | |||
| Histological diagnosis | ||||||||
| Adenocarcinoma | 152 | 25.5 | 445 | 74.5 | 0.660 | 1.00 | ||
| Mucinous carcinoma | 13 | 22.8 | 44 | 77.2 | 1.16[0.61-2.20] | |||
| Metastasis | ||||||||
| Absent | 138 | 24.0 | 436 | 76.0 | 0.751 | 1.00 | ||
| Present | 10 | 26.3 | 28 | 73.7 | 0.89[0.42-1.87] | |||
| Differentiation | ||||||||
| Low grade | 106 | 23.2 | 351 | 76.8 | 0.175 | 1.00 | ||
| High grade | 19 | 31.1 | 42 | 68.9 | 0.67[0.37-1.20] | |||
| Vascular invasion | ||||||||
| Absent | 127 | 25.1 | 378 | 74.9 | 0.490 | 1.00 | ||
| Present | 9 | 20.5 | 35 | 79.5 | 1.31[0.61-2.79] | |||
| Perineural invasion | ||||||||
| Absent | 112 | 24.2 | 350 | 75.8 | 0.042 | 1.00 | 0.051 | 1.00 |
| Present | 29 | 34.9 | 54 | 65.1 | 0.60[0.36-0.98] | 0.57[0.32-1.00] | ||
| Carcinoembryonic antigen (CEA) | ||||||||
| Normal (0-5) | 105 | 25.5 | 306 | 74.5 | 0.722 | 1.00 | ||
| Abnormal (>5) | 44 | 27.0 | 119 | 73.0 | 0.93[0.61-1.40] | |||
| Cancer antigen 19-9 | ||||||||
| Normal [1−37] | 70 | 21.6 | 254 | 78.4 | 0.133 | 1.00 | ||
| Abnormal [>37] | 14 | 31.8 | 30 | 68.2 | 0.59[0.30-1.17] | |||
| Prior screening | ||||||||
| No | 148 | 27.5 | 390 | 72.5 | 0.025 | 1.00 | ||
| Yes | 15 | 16.3 | 77 | 83.7 | 1.95[1.09-3.49] | |||
| First line of treatment | ||||||||
| Surgery | 56 | 20.8 | 213 | 79.2 | 0.067 | 1.00 | ||
| Chemotherapy | 76 | 29.0 | 186 | 71.0 | 0.64[0.43-0.96] | |||
| Radiotherapy | 38 | 28.6 | 95 | 71.4 | 0.66[0.41-1.06] | |||
* In multivariate logistic regression with a sample of 433 patients