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. 2016 Dec 24;8(22):36743–36749. doi: 10.18632/oncotarget.14151

Table 2. Results of the univariable and multivariablea analyses for OS.

Covariates Univariable analyses Multivariable analysis
HR 95% CI HR 95% CI
DT 1.02 0.91-1.14
DT
 <5 0.99 0.56-1.76
 ≥5b
Age 1.04 1.00-1.07 1.03 1.00-1.07
Sex
 Male Femaleb 0.71 0.41-1.22
Histology
 Adenocarcinomab
 Squamous cell carcinoma 1.72 0.95-3.13
 NSCLC otherwise not specified, adenomatous hyperplasia 1.33 0.31-5.71
 SCLC 1.01 0.43-2.39
CCI
 0-1 0.98 0.44-2.18
 > 2b
Treatment
 Surgery and (neo)adjuvant chemotherapyb
 Chemotherapy 1.45 0.57-3.71 1.43 0.56-3.66
 Chemotherapy and sequential/concurrent radiotherapy 6.87 2.16-21.85 6.34 1.99-20.19

aAll variables entered together in one block.

bReference group.

Abbreviations: OS, overall survival; HR, hazard ratio; 95% CI, 95% confidence interval; DT, distress thermometer score at first cycle of chemotherapy as a continuous variable; NSCLC, non-small cell lung carcinoma; SCLC, small cell lung carcinoma, CCI, Charlson Comorbidity Index.