Table 3. Clinical features and outcomes of six patients with perforations during endoscopic balloon dilation (EBD).
Patient no. | Age and sex | Tumor size, mm | Tumor location | Luminal circumference of tumor | Depth of tumor | Adjuvant chemoradiation | Prophylactic steroid injection | Type of steroid | Amount of total steroid administration, mg | Total number of EBD sessions | Max. diameter during EBD, mm | Clinical course after perforation | Hospital stay after perforation, days |
#1 | 70 M | 50 | U | ≥ 2 /3 | LPM | Absent | Absent | TA | 80 | 4 | 18 | Required surgery | 43 |
#2 | 61 M | 40 | U | < 2 /3 | MM | Absent | Present | TA | 80 | 1 | 18 | Cured by conservative management | 62 |
#3 | 75 F | 40 | U | ≥ 2 /3 | EP | Absent | Present | TA | 80 | 1 | 15 | Cured by conservative management | 77 |
#4 | 69 M | 37 | M | ≥ 2 /3 | MM | Absent | Present | DEX | 20 | 20 | 15 | Cured by conservative management | 55 |
#5 | 74 M | 58 | L | ≥ 2 /3 | LPM | Absent | Present | TA | 480 | 2 | 18 | Required surgery | 218 |
#6 | 68 M | 52 | U | ≥ 2 /3 | SM 700 μm | Absent | Present | TA | 785 | 186 | 16.5 | Cured by conservative management | 107 |
The six patients were from Osaka University Hospital, Osaka General Medical Center, Osaka National Hospital, and Toyonaka Municipal Hospital. U, upper-third esophagus; M, middle-third esophagus; L, lower-third esophagus; EP, epithelium; LPM, lamina propria; MM, muscularis mucosa; SM, submucosa. TA, triamcinolone acetonide; DEX, dexamethasone sodium phosphate.