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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Brain Behav Immun. 2017 Feb 3;64:320–329. doi: 10.1016/j.bbi.2017.02.001

Figure 3.

Figure 3

Alcohol-induced impairment of operant reversal learning and its prevention by pioglitazone. (A) Alcohol, pioglitazone (60 mg/kg) or the combined treatment did not influence operant learning of the initial task. (B) Performance in the reversal task was reduced in alcohol exposed while pioglitazone (60 mg/kg) prevented alcohol-induced impairment of reversal learning. Data are expressed as mean ±SEM percent (%) of correct responses (N=53, 12–14 per group). #p<0.05 vs control (CON) group receiving vehicle (PIO 0-CON); *p<0.05 vs alcohol group receiving vehicle (PIO 0-ALC). For detailed statistics, see “Results”.