Fig. 8.3.

Relative to low-altitude deer mice, high-altitude mice have higher expression of PPARγ protein (a) and mRNA (b) in the gastrocnemius muscle. Population-of-origin (i.e., high- or low-altitude) had significant main effects on PPARγ protein abundance and transcript abundance, but acclimation environment only had a significant main effect on protein abundance. There was no significant interaction between population-of-origin and acclimation treatment in either case [35]. The inset image in panel A shows representative immunoreactive bands for a high-altitude mouse (left) and low-altitude mouse (right) after acclimation to hypoxia. Modified from [35]