Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jun 23;7:4153. doi: 10.1038/s41598-017-03592-1

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

TrkB Fc reduces the levels of BDNF present in CM. (A) HUCPVC conditioned media was incubated with TrkB Fc and the levels of BDNF were determined by the Bioplex-Luminex assay. Our results show that TrkB Fc is able to cause a reduction of approximately 25% in the levels of BDNF in CM (74.37 ± 1.86), comparatively to CM (100.0 ± 3.35) proving that TrkB Fc is able to significantly deplete BDNF from CM. (B) BDNF concentration in CM is 37 pg/ml. On the other hand, the presence of TrkB Fc, reduces the levels of BDNF present in CM to approximately 27 pg/ml. BDNF levels were measured using a MILLIPLEX Kit. *Represents p = 0.0216 by Mann Whitney unpaired t-test when compared to CM.