Table 1.
Participants’ baseline characteristics at the beginning of each study period (n = 20).
| Parameters | Low AGE group | High AGE group | P-value |
|---|---|---|---|
| Weight (kg) | 94.2 ± 15.2 | 94.1 ± 14.3 | 0.94 |
| Body mass index (kg/m2) | 31.4 ± 3.8 | 31.3 ± 3.7 | 0.85* |
| % body fat | 30.7 ± 6.5 | 30.6 ± 6.6 | 0.83 |
| Waist-to-hip ratio | 0.9 ± 0.07 | 0.9 ± 0.07 | 0.35* |
| Systolic BP (mm Hg) | 123.1 ± 10.8 | 122.3 ± 12.3 | 0.66 |
| Diastolic BP (mm Hg) | 77.9 ± 8.9 | 76.7 ± 9 | 0.38 |
| Mean arterial pressure (mm Hg) | 92.9 ± 9.1 | 91.9 ± 9 | 0.37 |
| Pulse pressure (mm Hg) | 45.1 ± 6.4 | 45.6 ± 10.1 | 0.90* |
| Total cholesterol (mmol/l) | 4.8 ± 1 | 4.6 ± 1 | 0.06 |
| LDL (mmol/l) | 3.1 ± 0.8 | 3.1 + 0.7 | 0.61 |
| HDL (mmol/l) | 1 ± 0.2 | 1 ± 0.2 | 0.35 |
| Triglycerides (mmol/l) | 1.5 ± 1 | 1.3 ± 0.7 | 0.11* |
| CRP (mg/l) | 2.1 ± 1.9 | 2.4 ± 2.7 | 0.69* |
| TNFα (pg/ml) | 2.8 ± 3.7 | 1.6 ± 0.9 | 0.18 |
| MCP-1 (pg/ml) | 126 ± 99 | 121 ± 66 | 0.92* |
| IL-6 (ng/ml) | 1.5 ± 2.2 | 1.6 ± 2.4 | 0.64* |
| NFκβ p65 activity (ng/µg protein) | 14 ± 10 | 12 ± 10 | 0.53 |
All values are presented as means ±SDs. Paired t-tests were conducted to determine the p-values. *Data transformation was done. BP, blood pressure; CRP, C-reactive protein; HDL, high-density lipoprotein; IL-6, interleukin -6; LDL, low-density lipoprotein; MAP, mean arterial pressure; MCP-1, monocyte chemoattractant protein-1; NFκβ; Nuclear factor kappa beta; PP, pulse pressure.