Table 4.
The effects of interval and continuous exercise regimens on dynamic thrombin generation in platelet-rich plasma.
| HIT | MCT | CTL | ||||
|---|---|---|---|---|---|---|
| Pre | Post | Pre | Post | Pre | Post | |
| Vehicle | ||||||
| Lag time (min) | ||||||
| R | 9.1 ± 0.1 | 9.0 ± 0.1 | 9.1 ± 0.2 | 8.9 ± 0.1 | 9.1 ± 0.2 | 9.1 ± 0.2 |
| HE | 9.1 ± 0.1 | 9.0 ± 0.1 | 9.2 ± 0.1 | 8.9 ± 0.1 | 9.2 ± 0.2 | 9.3 ± 0.2 |
| ETP (mM × min) | ||||||
| R | 879 ± 25 | 876 ± 24 | 873 ± 14 | 871 ± 15 | 855 ± 25 | 885 ± 25 |
| HE | 1105 ± 34* | 845 ± 6+ | 1101 ± 35* | 870 ± 14+ | 1103 ± 42* | 1139 ± 48* |
| Peak height (mM) | ||||||
| R | 50.7 ± 1.7 | 45.5 ± 1.2 | 52.2 ± 1.3 | 49.6 ± 1.4 | 50.3 ± 3.7 | 51.0 ± 1.2 |
| HE | 70.1 ± 3.2* | 45.0 ± 1.3+ | 67.6 ± 2.5* | 49.1 ± 1.7+ | 71.6 ± 5.1* | 76.3 ± 2.9* |
| Oligomycin | ||||||
| Lag time (min) | ||||||
| R | 8.9 ± 0.1 | 9.0 ± 0.1 | 8.9 ± 0.1 | 8.8 ± 0.1 | 8.8 ± 0.2 | 8.7 ± 0.2 |
| HE | 8.8 ± 0.1 | 8.9 ± 0.1 | 8.8 ± 0.1 | 8.7 ± 0.1 | 8.8 ± 0.2 | 8.9 ± 02 |
| ETP (mM × min) | ||||||
| R | 779 ± 31 | 795 ± 17 | 791 ± 17 | 791 ± 14 | 795 ± 25 | 782 ± 20 |
| HE | 825 ± 32 | 788 ± 29 | 845 ± 18 | 803 ± 17 | 846 ± 25 | 834 ± 41 |
| Peak height (mM) | ||||||
| R | 45.0 ± 1.2 | 44.7 ± 1.6 | 45.3 ± 1.2 | 44.3 ± 1.6 | 44.2 ± 3.0 | 43.7 ± 1.2 |
| HE | 47.0 ± 1.3 | 44.0 ± 1.5 | 46.8 ± 1.2 | 44.0 ± 1.4 | 46.2 ± 3.0 | 44.9 ± 1.0 |
| Carbonyl cyanide-p-trifluoromethoxyphenylhydrazone | ||||||
| Lag time (min) | ||||||
| R | 6.9 ± 0.2 | 7.0 ± 0.1 | 6.9 ± 0.2 | 7.0 ± 0.1 | 7.0 ± 0.3 | 6.9 ± 0.2 |
| HE | 6.7 ± 0.2 | 7.0 ± 0.1 | 6.9 ± 0.2 | 6.9 ± 0.1 | 6.9 ± 0.2 | 7.1 ± 0.2 |
| ETP (mM × min) | ||||||
| R | 1005 ± 23 | 955 ± 22 | 1027 ± 25 | 1032 ± 21 | 1069 ± 28 | 1040 ± 26 |
| HE | 1222 ± 28* | 951 ± 20+ | 1215 ± 32* | 1025 ± 18+ | 1252 ± 30* | 1243 ± 33* |
| Peak height (mM) | ||||||
| R | 78.1 ± 3.4 | 79.2 ± 2.9 | 82.6 ± 2.8 | 76.8 ± 2.9 | 83.6 ± 6.1 | 87.3 ± 2.1 |
| HE | 108.1 ± 3.4* | 78.6 ± 1.7+ | 106.5 ± 2.7* | 79.4 ± 2.62+ | 111.7 ± 7.2* | 112.5 ± 4.8* |
| Rotenone plus Antimycin A | ||||||
| Lag time (min) | ||||||
| R | 9.0 ± 0.2 | 9.0 ± 0.1 | 9.1 ± 0.2 | 8.8 ± 0.1 | 9.0 ± 0.2 | 8.7 ± 0.2 |
| HE | 8.9 ± 0.2 | 8.9 ± 0.1 | 9.0 ± 0.1 | 8.8 ± 0.1 | 9.0 ± 0.2 | 8.8 ± 0.3 |
| ETP (mM × min) | ||||||
| R | 833 ± 22 | 723 ± 21+ | 840 ± 31 | 749 ± 16+ | 833 ± 20 | 829 ± 26 |
| HE | 847 ± 20 | 735 ± 21+ | 879 ± 27 | 754 ± 13+ | 859 ± 24 | 841 ± 24 |
| Peak height (mM) | ||||||
| Rest | 49.0 ± 2.1 | 33.3 ± 0.9+ | 45.3 ± 1.8 | 34.7 ± 1.3+ | 46.4 ± 3.0 | 47.0 ± 1.3 |
| HE | 50.4 ± 1.7 | 32.6 ± 1.0+ | 48.1 ± 1.5 | 37.0 ± 1.8+ | 49.8 ± 3.1 | 47.8 ± 1.5 |
Values were mean ± SEM. HIT, high-intensity interval training group; MCT, moderate-intensity continuous training group; CTL, control group; Pre, pre-intervention; Post, post-intervention; R, resting; HE, hypoxic exercise test; ETP, endogenous thrombin potential. *P < 0.05, R vs. HE; + P < 0.05, Pre vs. Post.