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. 2017 Jun 23;7:4148. doi: 10.1038/s41598-017-04176-9

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Gene sets enrichment analysis delineates associated with KIF4A expression level in the TCGA liver cancer cohort. Several cancer related signaling pathways were significantly enriched in the high-KIF4A group (a), such as cell cycle (b), DNA replication (c), homologous recombination (d) and p53 signaling (e) pathway. Normalized enrichment score (NES) is used to evaluate enrichment result. The –log p indicates the -log 10 transformed FDR p value of the corresponding pathway.