Table 3.

Tyrosine phosphoryation of Irs proteins

	Irs1		Irs2		Irs3		Irs4
Species	Ya	pYb	Y	pY	Y	pY	Y	pY
Mouse	34	20	36	21	17	10	29	13
Rat	35	22	36	21	18	13	30	17
Golden hamster	34	20	37	20	14	8	31	15
Prairie vole	34	21	37	20	17	11	34	13
Prarie deer mouse	34	20	37	20	18	12	27	15
Coqurel’s sifka	34	20	38	21	16	7	33	15
Mouse lemur	34	20	38	20	16	8	31	16
Mouflon sheep	34	19	38	20	14	8	30	15
Killer whale	33	20	38	21	17	8	28	15
Xenopus tropicalis	32	22	31	17	25	16	39	24
Average	33.8	20.4	36.6	20.1	17.2	10.1	31.2	15.8
Conservedc	27	16	25	13	10	5	17	9

^aNumber of tyrosine residues in the sequence

^bNumber of tyrosine residues predicted to be phosphorylated

^cNumber of residues conserved across the 10 sequences