Fig. 5.
NAC treatment partially rescues folliculogenesis in Kat8Gdf9 cKO females. (A) Ovaries from 3-week-old PBS- or NAC-treated mice. (B) Ratio of ovary weight to body weight in 3-week-old mice. (C) MII oocytes from 3-week-old mice. (D) Mean number of MII oocytes collected from each female following superovulation with PMSG and HCG. (E) Ovary sections from 3-week-old mice stained with Hematoxylin and PAS. Boxed regions are magnified beneath. (F) Quantitative analysis of follicles at different stages in ovary sections from PBS- or NAC-treated mice. (B,D,F) Data are mean±s.e.m. from three independent experiments. *P<0.05, **P<0.01, ***P<0.001, one-way ANOVA. Images (A,C,E) are representative of three independent experiments. Scale bars: 0.5 mm in A; 100 μm in C; 200 μm in E.