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. 2017 Jun 15;144(12):2175–2186. doi: 10.1242/dev.152025

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© 2017. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 5. — Arp2/3 complex localization and function in wild-type and vpr-1 mutant muscles. (A) ARX-2 localization at the muscle myofilament, visualized using a functional myo-3p::arx-2::mCherry transgene and myo-3p::moesin::GFP transgene that labels actin. ARX-2::mCherry puncta lie between thin filaments, possibly at dense bodies. (B) ARX-2::mCherry and mitoGFP localization in adult wild-type and vpr-1 mutant muscle. Columns show different depths of view, starting at the myofilament. The muscle belly lies 1-3 μm beneath myofilaments. (C) Representative results from the suppressor screen showing arx-2 RNAi and smn-1 RNAi. Asterisk, nucleus. Scale bars: 5 µm in A; 10 µm in B,C.