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. 2017 Jun 15;144(12):2175–2186. doi: 10.1242/dev.152025

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© 2017. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 6. — SMN-1 functions in body wall muscle. (A) Mitochondria visualized with mitoGFP in smn-1(ok355) mutant muscle. smn-1(ok355) hermaphrodites arrest development around the L3 stage when maternal smn-1 runs out (Briese et al., 2009). (B) Muscle mitochondria in smn-1(ok355) mutants expressing smn-1::mCherry specifically in muscle. The top two panels are from the same L4 stage hermaphrodite; the bottom three panels are from different adult hermaphrodites. Some transgenic mutants are able to progress to L4 and young adult stages and contain embryos (E), which are not seen in nontransgenic smn-1(ok355) mutants. (C) Mitochondria in adult muscle following muscle-specific smn-1 RNAi using sid-1 mutants. Asterisk, nucleus. Scale bars: 5 µm in A,C; as indicated in B.