Fig. 6.

Working model of rice PRXs for regulatory pathway using refined protein–protein interaction network. Predictions were made with RIV, which revealed interactions with 161 proteins mediated by four PRX proteins. Red edges (lines) indicate elements with PCC values >0.5; large rectangles in node, three interaction proteins with known functions identified from OGRO database; large circles, PRX family members; medium circles, interactors showing multiple interactions with PRX proteins. MapMan annotation is indicated by different node colors: bright green, redox class proteins, including peroxiredoxins and thioredoxins; pale blue, proteins involved in amino acid metabolism; yellow, proteins involved in cell cycle, lipid metabolism, photosynthesis, and development; blue, proteins involved in DNA synthesis and repair; pink, proteins involved in protein degradation and post-translational modification; purple, proteins involved with RNA, mostly transcriptional regulators; brown, signaling proteins; gray, abiotic stress proteins; light blue, transporter class proteins; green, proteins with unknown functions (see Additional file 11: Table S7).