Fig. 2.

Hemin-induced ICH injury is attenuated in TLR2 KO mice. a-b Hemin-injected WT and TLR2 KO mouse brain sections were used for cresyl violet staining to measure brain damage. Scale bar: 1 mm. The injury volume (mm³) was calculated by multiplying the section thickness by the injured hemorrhagic area (* p < 0.05 vs. hemin-injected WT mice). c At 24 h after hemin administration, the neurological deficits were evaluated in the WT (n = 5) and TLR2 KO (n = 5) mice (** p < 0.01 vs. hemin-injected WT mice, *** p < 0.001 vs. control mice). For all graphs, the data are presented as mean ± SEM